10-Hydroxy-2-Decenoic Acid is a kind of special active substance which exists only in royal jelly in the nature. It is also called 10-HDA. The content of 10-HDA is the international standard of the quality of royal jelly and it directly determines the price of royal jelly on the international market.10-HDA is of significant value in medical and health care domains. (1)10-HDA prevents the loss of leukocyte during the chemical treatment. (2)10-HDA can be absorbed by human body easily. It can also protect the skin and make the skin beautiful efficiently. (3)10-HDA possesses strong inhibition to the growth of cancer cells, namely transferable AKR leukaemia, TA3 breast cancer etc. Recent studies show that 10-HDA possesses the effect of immuno-regulation and anti-cancer activities.